Tebuconazole is a triazole fungicide introduced into the market by Bayer. It has excellent biological activity, low dosage, strong systemicity, and a wide range of applications. It is resistant to powdery mildew, stalk rust fungus, ceratocystis, Diseases caused by Sclerotium and Needle spores can be effectively prevented.

Synthesis of Tebuconazole Technical:

The current tebuconazole process mainly consists of the following processes:

1) Synthesis of 4,4-Dimethyl-1-(4-chlorophenyl)-3-pentanone (“pentanone” for short) through pinacolone and p-chlorobenzaldehyde

2) Cyclization of pentanone to obtain ethylene oxide derivatives;

3) Tebuconazole is obtained from ethylene oxide derivatives and triazole.

In the above reaction process, pentanone is a core intermediate. At present, some companies rely on outsourcing. At the same time, the main raw materials for pentanone synthesis, pinacolone and p-chlorobenzaldehyde, have a large market price fluctuation, which leads to the tension of pentanone supply. 

Beijing Yibai Biotechnology Co., Ltd is producing pentanone now, regular stable stock ecch month is 50MT.